Week 2 of the NFL season delivers a crucial AFC showdown as the Jacksonville Jaguars head north to battle the Cincinnati Bengals. Both teams enter the contest with playoff aspirations, and this matchup could carry tiebreaker implications later in the year. Trevor Lawrence and the Jaguars’ offense look to stay sharp against a Bengals defense adjusting to life without a few key veterans, while Joe Burrow and Cincinnati aim to bounce back after a slow Week 1 start.
With Cincinnati opening as a slight home favorite and the total hovering around the mid-40s, Sunday’s clash offers a variety of enticing prop betting opportunities. Let’s dive into the
Top 4 Prop Bets
for this game.
Today’s Top Prop Bets at a Glance
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Trevor Lawrence Over 259.5 Passing Yards
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Ja’Marr Chase Anytime Touchdown
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Joe Mixon Over 66.5 Rushing Yards
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Evan Engram Over 4.5 Receptions
Trevor Lawrence Over 259.5 Passing Yards
Trevor Lawrence looked sharp in Week 1, spreading the ball efficiently across multiple targets, including Calvin Ridley and Christian Kirk. The Bengals secondary is still working in young players after losing veterans in free agency, and their struggles in coverage were evident last week. Lawrence has averaged 263 passing yards per game over his last eight outings, and with Jacksonville likely to push the tempo, this line of 259.5 sets up favorably. Expect Lawrence to clear this number if game script leans pass-heavy.
Tip: Bet Lawrence Over 259.5 Yards
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Jaguars Pass Heavy
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Bengals Secondary Issues
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Lawrence in Form
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Ja’Marr Chase Anytime Touchdown
Joe Burrow’s favorite weapon, Ja’Marr Chase, is always a threat to score. Chase was quiet in Week 1 by his lofty standards, but history shows he rarely stays quiet two weeks in a row. Jacksonville’s secondary has allowed explosive plays downfield, and Chase’s ability to create separation makes him a prime red-zone option. In front of the home crowd, look for Burrow to feed Chase early and often, making an Anytime TD bet a strong value play.
Tip: Bet Chase Anytime TD
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Burrow Connection
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Red Zone Target
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Joe Mixon Over 66.5 Rushing Yards
The Bengals need to establish balance, and Joe Mixon remains their workhorse back. Jacksonville’s front seven can be stingy, but they’ve allowed over 4.3 yards per carry across their last five games. Mixon logged 18 carries in the opener, and volume is the key here—if Cincinnati plays with a lead, his workload should only increase. At 66.5 yards, this prop sits within reach for a player capable of breaking one big run to tilt the numbers.
Tip: Bet Mixon Over 66.5 Yards
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Bengals Balance
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Heavy Volume
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Breakaway Potential
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Evan Engram Over 4.5 Receptions
The Jaguars’ tight end Evan Engram quietly remains one of Trevor Lawrence’s most trusted targets. In Week 1, he was heavily involved on third downs and in the short passing game. Cincinnati linebackers have had issues covering athletic tight ends, making Engram an ideal candidate to clear 4.5 receptions. If the Bengals bring pressure, quick throws to Engram will help neutralize the rush, boosting his reception totals in the process.
Strategy Tip
Pairing
Lawrence Over 259.5 Passing Yards
with
Engram Over 4.5 Receptions
makes sense in a pass-heavy script. On the flip side, correlating
Mixon Over 66.5 Yards
with
Chase Anytime TD
reflects a Bengals-controlled game plan. Mixing these scenarios helps balance exposure and provides multiple paths to profit depending on how momentum shifts.
Bonus Props Worth Watching
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Calvin Ridley Over 69.5 Receiving Yards
– Emerging as Lawrence’s top deep threat.
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Joe Burrow Over 1.5 Passing TDs
– At home, primed for a rebound performance.
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First Half Over 21.5 Points
– Both offenses have explosive upside early.
Final Thoughts
The Jaguars vs. Bengals matchup offers star power on both sides, with Burrow and Lawrence set to headline a pivotal Week 2 contest. Prop value emerges through Lawrence’s passing upside, Chase’s scoring potential, Mixon’s steady workload, and Engram’s role as a safety valve. With two talented offenses facing off in a high-leverage AFC tilt, bettors should expect fireworks and plenty of chances to cash tickets on Sunday.
