Here’s a comprehensive betting preview for tonight’s Chargers vs. Lions Hall of Fame Game on Thursday, July 31, 2025, at 8 p.m. ET from Canton, Ohio, on NBC
Los Angeles Chargers vs Detroit Lions
Point Spread: Lions -1.5
Moneyline Lions -135
Moneyline Chargers +110
Over/Under 32.5
🔍 Team & Game Context
Los Angeles Chargers
Justin Herbert sits out; Trey Lance expected to start into the third quarter, followed by DJ Uiagalelei or Taylor Heinicke.
Offense leans into rookie talents: Omarion Hampton (RB), Tre Harris, KeAndre Lambert‑Smith gaining early reps.
The coaching staff under Jim Harbaugh favors a run-heavy, physical identity; the defense is still strong despite losing Joey Bosa.
Detroit Lions
Coming off a franchise‑best 15‑2 season, though, both coordinators have been replaced this offseason (Ben Johnson & Aaron Glenn departed).
Jared Goff is likely inactive; snaps are expected from Hendon Hooker and Kyle Allen, with depth players like Tate Ratledge and Tyleik Williams also likely as surprises.
Dan Campbell is managing starter usage; most vets will not play, reserving evaluation for depth and scheme integration.
Chargers vs Lions Moneyline
Chargers have multiple QBs eager to prove themselves; rookies getting significant reps can tilt upside toward L.A.
Underdogs have won the HOF Game the last three seasons, making this type of pick more appealing
. To find the best line, you need accounts with multiple sportsbooks, and we got you covered as we break down the
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DraftKings
4.5/5
Tip: Bet Chargers +1.5
Chargers to play more starters
Turnovers to be key
Game in Canton
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Chargers vs Lions Over/Under 32.5
Last three HOF Games: 37+ combined points each, despite low preseason totals set at ~32.5–33.
Public overwhelmingly betting the
Over; this trend lines up with expert picks advocating an over result again
DraftKings
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Tip: Bet the Over 32.5
Chargers to play the better QBs
Chargers style more conducive to Preseason
Game in Canton
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🎯 Final Pick(s)
Primary:
Over 32.5 (+110)
— expect atypical scoring bursts even in preseason settings.
Secondary:
Chargers moneyline at +115
— strong upside play as underdogs with motivational edge on roster cut auditions.
⚠ Key Notes & Caveats
Starter availability
is low: both teams treating this as depth showcase rather than full competitive tilt.
Limited regular-season inference: performance tonight may be more indicative of camp battles than true season form.
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