NFL Week 15 Buffalo Bills vs Detroit Lions: Odds, Tips and Predictions 12-15-24

This is a possible Super Bowl preview, as these two teams are as good as any in the NFL. Jared Goff and Josh Allen are both playing like they are the MVP of the league, and while both teams have some weaknesses, they are few and far between.

Buffalo Bills vs Detroit Lions

• Point Spread: Lions -2.5
• Moneyline Bilss +122
• Moneyline Lions -144
• Over/Under 54.5

On a strategic and offensive level, this game will play in Jared Goff’s play-action’s favor. Buffalo ranks near the bottom when it comes to first down run defense and on first-and-10 carries with an average 5.0 yard per carry allowed; by contrast, Detroit allows just 4.1 yards per carry, placing them among the top 10. The Lions are hitting explosive runs (10 yards or more) more often than any other team’s run defense can.

That puts the Bills defense in an awkward situation: If they dedicate more resources to slowing Jahmyr Gibbs and David Montgomery on early downs, Goff has been highly effective with play action, which opens up significant matchup advantages for Amon-Ra St. Brown, Tim Patrick, Sam LaPorta as intermediate-range receivers off play action – not to mention Jameson Williams a as deep threat with Buffalo starting CB Rasul Douglas out due to injury.

But while Buffalo may worry about Detroit’s arsenal of passing game weapons, Detroit offensive line and Sonic and Knuckles combo can run around and past lighter fronts with ease. Goff and offensive coordinator Ben Johnson have proven adept at exploiting any advantages given by any defense; with Taylor Decker back at left tackle more opportunities are opening up for runs and screens on that side; making Detroit even harder to defend!

Special teams, from kicker and punter to return man and coverage, could be an asset for Detroit in this game. Brandon Codrington is an effective punt returner but rarely sees consistent blocking by Buffalo; Tyler Bass’s kicks are only 50/50 between 40 and 50 yards but have netted him one 61-yarder this year! Additionally, Dave Fipp’s Detroit special teams units and Dan Campbell’s “play to win” motto may play into Detroit’s favor in this contest.

On defense, the Lions man coverage on the outside was clearly superior to that of the Bills receiving corps at getting open. Don’t take this as evidence that their receivers don’t possess talent – like Khalil Shakir and recently acquired Amari Cooper, who remains a legitimate threat – it simply shows their passing game is more focused on tight throws and breaking tackles rather than creating open runners and forcing blown coverages; creating space for playmaking safeties like Kerby Joseph and Brian Branch to make big plays themselves.

A more balanced defensive front can help Detroit’s pass rush, too. Receiving DJ Reader and Josh Paschal back is great news because they are Detroit’s run-responsible defensive linemen – they make for great run defense! Instead of heavily relying on sacks or pressures as an offensive tactic, this one aims to contain Josh Allen by making him uncomfortable and impatient – readers and Alim McNeill occupying the front pocket will deny Allen easy escape routes or open running lanes to provide him with quick escape routes or open running lanes easily!

Bills vs Lions Moneyline

Moneyline value exists with both teams in what should be a tight game.To find the best line, you need accounts with multiple sportsbooks, and we got you covered as we break down the best sports betting app

DraftKings

4.5/5

Tip: Bet Lions -2.5

• Goff to play well
• Lions run game will be exlposive
• Lions at home

New DraftKings Customers: Spend $5+ Get $150 in Bonus Bets *Paid Within 14 Days

Open DraftKings

The best NFL betting sites

To satisfy the ever-growing market of NFL bettors, the best football sportsbooks offer unique user experiences, huge payouts, and fantastic bonuses. Gamers no longer have to go to casinos to find some physical action. Online bookies let you play the game of risk from the comfort of your own home. We hope our guide can point you in the right direction so you can find the best gambling experiences on the internet.

Best Brand

FanDuel Promo

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Get bonus now

Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET. Call 1-888-789-7777 or visit ccpg.org/chat (CT). Hope is here. GamblingHelplineMA.org or call (800) 327-5050 for 24/7 support (MA). Visit www.mdgamblinghelp.org (MD). Call 1-877-HOPENY or text HOPENY (467369) (NY). 21+ (18+ DC, IA, KY, WV) only. New users only or text HOPENY (467369) (NY). Casino, First online real money wager only. $5 first deposit required. Min $5 wager required for 5 consecutive days. Bonus issued as non-withdrawable Bet Reset tokens. Refund from token issued as nonwithdrawable bonus bet that expire 7 days after receipt. Max refund $200 per day. Restrictions apply, including token expiration. See full terms at fanduel.com/sportsbook. Call 1-877-770-7867 (LA).

Best Slots

BetMGM Promo

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Get bonus now

Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.

Newcomer

DraftKings Promo

New DraftKings Customers: Spend $5+ Get $150 in Bonus Bets *Paid Within 14 Days

Get bonus now

GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). 21+ and present in most states. (18+ DC/NH/PR/WY). Void in CAN. Eligibility restrictions apply. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL. 1 per new DraftKings customer. $5+ first-time bet req. Max. $150 issued as non-withdrawable Bonus Bets that expire in 7 days after issuance. Stake removed from payout. Reward issued as $50 in Bonus Bets every 7 days via click-to-claim for 14 days. 7 days = 168hrs. Terms: sportsbook.draftkings.com/promos. Ends 8/23/26 at 11:59 PM ET. Sponsored by DK.

Award

Caesars Promo

Bet $1 and get double the winnings up to $25 for your next 10 bets

–

21+ New users only. Must register using eligible promo code. First bet after registration must qualify. Max. Bonus Bet: $1,000. Bonus Bet expires 14 days after receipt. Void where prohibited. See Caesars.com/promos for full terms. Gambling Problem? 1-800-GAMBLER (1-800-426-2537)

Bills vs Lions Over/Under Analysis

Hit the over on this one, both Quarterbacks are elite and both teams can run the ball. This should be a game played at least in the mid-gigh 20s.

DraftKings

4.5/5

Tip: Bet Over 54.5

• Lions play-action will be deadly
• Bills must run the ball
• Lions better all around team

New DraftKings Customers: Spend $5+ Get $150 in Bonus Bets *Paid Within 14 Days

Open DraftKings

Prediction: Play-action puts the Lions offense over the top in this game. Lions 31  Bills 27