College Football Missouri vs Vanderbilt: Top 4 Prop Bets

This Saturday’s SEC East battle in Nashville features two programs on different trajectories.

The Missouri Tigers (6-1, 3-1 SEC) are operating with transfer signal-caller Beau Pribula at the helm, having taken over after an early injury at the position. Meanwhile, the Vanderbilt Commodores (2-5, 0-4 SEC) are led by dual-threat quarterback Diego Pavia, whose arm and legs both create problems for opposing defenses.

Missouri’s offensive rhythm under Pribula gives them a clear talent and execution edge, while Vanderbilt will lean on Pavia’s improvisational ability and home crowd to make noise. The Tigers’ coaching continuity under Eli Drinkwitz also favors them in what could become a one-sided outing.

🏈 Prop Overview

Matchup: Missouri Tigers at Vanderbilt Commodores Location: FirstBank Stadium (Nashville, TN) Kickoff: Saturday, 7:30 PM ET Spread (est’d): Vandy -2.5 Total (est’d): 52.5

🐯 1) Beau Pribula – Over 285.5 Passing Yards

Pribula, a graduate transfer from Penn State, has already shown he’s capable of moving the ball efficiently through the air for Missouri.  Vanderbilt’s secondary has been tested this season and gives up chunk plays. With the Tigers likely to attack vertically, this line feels reachable.

BetMGM

4.9/5

Tip: Best Odds for Pribula Over 285.5 Passing Yards

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🔥 2) Diego Pavia – Over 1.5 Total Touchdowns (Passing + Rushing)

Pavia’s dual-threat nature makes this prop intriguing. Last season he accounted for significant rushing yards in addition to his passing contributions. SI+1 Vanderbilt may need to rely on his scrambling and improvisation to keep pace. Betting on at least two total TDs (throw or run) gives upside.

Caesars

4.7/5

Tip: Best Odds for Pavia Over 1.5 Total TDs

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🧱 3) Luther Burden III – Over 89.5 Receiving Yards

Burden continues to be Missouri’s top receiving threat, and with Pribula likely spreading the ball around, Burden should see favorable matchups and target volume. Given Vanderbilt’s secondary issues, surpassing ~90 yards feels very attainable.

FanDuel

4.6/5

Tip: Best Odds for Burden Over 89.5 Yards

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⛅ 4) Game Total – Under 58.5 Points

Although both teams have offensive capability, this number seems inflated considering Vanderbilt’s inconsistent drive-sustain and Missouri’s ability to control tempo when ahead. If the Tigers build an early lead, expect clock-management and fewer big scoring drives. Lean Under.

DraftKings

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Tip: Best Odds for Under 58.5 Total

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💰 Betting Strategy & Final Thoughts

The strongest play is likely pairing Pribula Over with Burden Over for the Missouri passing stack. Pavia’s TD prop gives Vanderbilt upside in case of a fast start, while the Under 52.5 covers.

Final Score Prediction: Vandy 27 Missouri 20 Favorite Props: Pribula Over, Burden Over, Pavia Over TDs, Under 52.5