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The Grueling Truth - Where Legends Speak / Betting Tips / CFP First Round Playoff: No. 6 Ole Miss vs. No. 11 Tulane

CFP First Round Playoff: No. 6 Ole Miss vs. No. 11 Tulane: Preview, Prediction and Top prop Bets

NCAAF Betting Tips · - ·

Publish Date: 12/18/2025
Fact checked by: Mike Goodpaster

Date: Saturday, December 20, 2025 • Time: 3:30 PM ET (2:30 PM CT) Location: Vaught-Hemingway Stadium, Oxford, MS TV: TNT / TruTV / Max Atmosphere: Stripe Out (Red & Blue)

The Matchup at a Glance

#11 Tulane Green Wave (11–2)#6 Ole Miss Rebels (11–1) Offense Physical, run-first attack behind QB Jake Retzlaff (2,862 Pass Yds, 16 Rush TDs).Nation’s #3 offense (498.1 YPG) led by Trinidad Chambliss. Defense Top-30 vs the run; vulnerable vs the pass (#121 nationally).Landshark D with All-Americans Walter Nolen & Chris Paul Jr. Turnovers One of the best turnover teams (#11, +10 margin).Volatile (-2 margin, #81 in FBS). Key Player RB Jamauri McClure — breakout freshman (121 yards in AAC Title).RB Kewan Lacy — SEC TD leader (1,279 yards, 20 TDs).

The Coach Comparison: Stability vs. Succession

Jon Sumrall — Tulane

• Accepted the Florida job, but staying to finish Tulane’s CFP run. • Power-run identity, controlled tempo. • Made national news donating $100k to Tulane’s NIL fund this week.

Pete Golding — Ole Miss

• Promoted from DC after Lane Kiffin left for LSU. • Defensive aggression + explosive offensive philosophy. • Hired LSU legend Frank Wilson to fortify future recruiting.

Quarterback Breakdown

Trinidad Chambliss (Ole Miss)

The D-II transfer who became a superstar. Over 3,000 passing yards, 18 TDs, and 114 rushing yards in the first meeting vs Tulane. The engine of the #3 offense in America.

Jake Retzlaff (Tulane)

A physical dual-threat dubbed “The Sledgehammer.” School-record 16 rushing TDs, dangerous on designed QB power. Improved as a passer late in the season and has won 8 of his last 9.

Keys to the Game

For Ole Miss to Win:

• Avoid a post-Kiffin slump — keeping OC Charlie Weis Jr. is massive. • Attack Tulane deep early; their #121-ranked pass defense is the biggest mismatch of the CFP first round. • Let Lacy dictate the pace in the red zone.

For Tulane to Win:

• Control the “Middle Eight” (last 4 min of 1H + first 4 min of 2H). • Force turnovers — Ole Miss has struggled in this area all season. • Keep Chambliss off the field with long, punishing drives.

Weather & Betting Odds

Weather: 62°F, broken clouds — ideal conditions. Spread: Ole Miss -17.5 Over/Under: 56.5 Moneyline: Tulane +600 / Ole Miss -900

Top 4 Prop Bets for Ole Miss vs. Tulane

(Formatted exactly like the Alabama vs. Oklahoma preview)

1. Trinidad Chambliss Over 295.5 Passing Yards

Chambliss carved up Tulane in September and now faces one of the worst pass defenses in the nation. Ole Miss will push tempo and attack vertically off RPOs. If Tulane crowds the box, Chambliss could hit 300+ by late third quarter.

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  • Massive mismatch vs Tulane secondary
  • 307 yards in first meeting
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2. Kewan Lacy Anytime Touchdown

The SEC’s touchdown king (20 TDs) is the Rebels’ unquestioned red-zone hammer. He gets goal-line work, RPO looks, and screen opportunities. In a game where Ole Miss should live inside Tulane territory, Lacy scoring is the safest TD prop on the board.

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Tip: Kewan Lacy anytime touchdown
  • SEC TD leader
  • Red-zone focal point
  • High-scoring potential
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3. Tulane Team Rushing Yards Over 169.5

Tulane’s only path to staying competitive: shorten the game and run downhill behind Retzlaff and McClure. Expect 40+ rush attempts. Their QB-driven ground system stresses Ole Miss horizontally.

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Tip: Tulane rushing yards over 169.5
  • Run-first identity
  • Retzlaff + McClure combo
  • Must control tempo
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4. Total Combined Sacks Over 4.5

Ole Miss’ front seven is elite, and Tulane’s defense thrives on chaos and pressure. Both OL units have struggled against top-tier fronts. In a CFP slugfest, expect pressure constantly.

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Tip: Total sacks over 4.5
  • Elite Ole Miss front
  • Tulane pressure packages
  • Playoff intensity = more sacks
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Final Prediction

This game will be far more competitive than September’s matchup — Tulane is tougher, more disciplined, and emotionally rallied around a coach finishing the fight.

But Ole Miss has too much speed, too much explosiveness, and the home-field advantage of a deafening Stripe Out.

Prediction: Ole Miss 34, Tulane 20

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