UFC 280 Charles Oliveira vs. Islam Makhachev: Preview and Predictions

Odds for UFC 280

 — Fight Information

• 🥊 UFC Match:Charles Oliveira vs. Islam Makhachev
  
• 📅 Date: October 20th, 2022
• 🕛 Main Event Time: Approx 10.30 PM EST
• 🏆 Title: N/A
• 📺 TV Channel: PPV

Check out the top sportsbooks for betting on

4.6/5

FanDuel Review

New Users – Get $350 in Bonus Bets when you wager $5 for 7 days

Bet now

Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET. Call 1-888-789-7777 or visit ccpg.org/chat (CT). Hope is here. GamblingHelpLineMA.org or call (800) 327-5050 for 24/7 support (MA). Visit www.mdgamblinghelp.org (MD). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY). 21+ (18+ D.C., KY, WY) and present in select states (for KS, in affiliation with Kansas Star Casino). First online real money wager only. Min $5 wager required for 7 consecutive days.$5 first deposit required. Bonus issued as nonwithdrawable bonus bets which expire 7 days after receipt. Restrictions apply. See terms at sportsbook.fanduel.com. Call 1-877-770-7867 (LA). ™/© 2026 MLB

4.5/5

BetMGM Review

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Bet now

Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.

4.5/5

DraftKings Review

New DraftKings Customer: SPEND $5, GET $200 IN BONUSES

Bet now

To be eligible for DraftKings Sportsbook and the Promotion, you must be physically located in AR, AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA (select parishes), MA, MD, ME, MI, MO, NC, NJ, NH, NY, OH, OR, PA, PR (residents only), TN, VA, VT, WY, WV, CA-ONT or CA-AB (each an “Eligible Jurisdiction” or, collectively, the “Eligible Jurisdictions”). Must be 21+ years of age or older (18+ if in DC/NH/PR/WY/CA-AB) (19+ in CA-ONT). GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA) Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). 21+ and present in most states. (18+ DC/NH/PR/WY). Void in CAN. Eligibility restrictions apply. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL. 1 per new DraftKings customer. $5+ first-time bet req. Max. $200 issued as non-withdrawable Bonus Bets. Stake removed from payout. Reward issued as $50 in Bonus Bets every 7 days via click-to-claim for 21 days. Bonus Bets and click-to-claims expire 7 days (168hrs) after issuance. Terms: Promos | DraftKings Sportsbook . Ends 9/20/26 at 11:59 PM ET. Sponsored by DK.

Charles Oliveira vs. Islam Makhachev

We are excited about the +140 cash line for Oliveira. He has defeated top contenders Gaethje, Poirier and Charles back-to-back-to-back.  Makhacehv has fought only one fighter in the top ten, and two in the top fifteen. Charles has beaten #2, 3, 5. Charles will not be considered by TKO or Sub at +155 because it is just +15 above the money line. Bet on Oliveira wins with the easy money.

UFC 280 Picks — The Best Bets for Charles Oliveira vs. Islam Makhachev

Take Oliviera at +140 to win on the money line.

Bet on Oliveira at Caesars Sportsbook

Sports Promo

4.6/5

Sports Promo

4.6/5

New Users – Get $350 in Bonus Bets when you wager $5 for 7 days

Signup Promo

|

Open FanDuel

Get bonus now

Betting Strategies

The first tip here would be to do your research, as styles make fights. Also, look for similar styles matchups. Check out the top UFC odds.

Potential earnings

If you are betting on Oliveira in the main event, the payoffs will be significant, and I think he will win this fight. For example, the odds as of a few days before the fight are averaging out to Oliveira by more than +140 to win.  To me, the best bet on this fight is betting Oliveira to win, which gets you odds of +140, which on a 100-dollar bet pays 140 dollars, plus you get the 100 dollars you bet back.

Undercard fights

Aljamain Sterling -175 vs Tj Dillashaw +145

Dillashaw will be fighting for his seventh title. Sterling won via split decision in the first defense of his title in April. Dillashaw has the experience advantage and has competed at championship level more often than Sterling, but Sterling’s performance against Cory Sandhagen was much more impressive than expected. Dillashaw won a split-decision victory in the fifth round over Cory Sandhagen in July of last year.

Dillashaw has never been submitted in his UFC career. Dillashaw is an excellent grappler whose training footage before the Sterling fight prioritized grappling. Sterling has many advantages in this fight, including his age and momentum. Since 2017, the champion has won a record seven consecutive times. Dillashaw lost in 2016 and was defeated again in 2019. Dillashaw came back to win one fight last year.

Sterling Money Line

The UFC 280 odds support Sterling’s win in almost every category. Dillashaw isn’t able to handle the bantamweight cut well and is approaching forty.

Petr Yan -275 against Sean O’Malley -215

UFC 280 betting odds show O’Malley’s meteoric rise coming to an abrupt halt. Yan is ahead in betting odds wins by submission, points, and TKO. O’Malley is a knockout power fighter, but Yan has never been rocked or dropped in his MMA career.

O’Malley supporters should be worried about him facing the #3 Bantamweight. O’Malley has not met any top 15 fighters but is still #11. O’Malley has beaten Paiva (4-4 UFC) but has not won any other significant fights. It was upset that he lost to Vera in 2020. O’Malley’s ability to knock out any of the relevant athletes is still untested.

Yan wins easy

Although we aren’t sure if we will place a wager one way or another, the money line is great for parlay betting. Out of all the odds for Oliveira against Makhachev, this fight is the most one-sided. The fans don’t even know it yet.

Best Betting Site for UFC 280

Today we will give you our top 5 betting sites for betting on UFC 280. Check out the top UFC Betting sites.

BET Rivers

BetRiver’s reward program for loyal players is the iRush Rewards program. This multi-tiered offer offers ten levels of unique benefits and many other advantages. You’ll get access to the bonus store, custom deposit limits, and special BetRivers offers in the first six levels. You’ll be able to receive more rewards once you reach the seventh level, such as invitations to VIP events and birthday gifts. The program’s purpose is to enhance your sports betting experience.

We give the rewards program a 5-star BetRivers rating. This program is available to all players, regardless of whether they play at the casino or sportsbook. It applies to both desktop and mobile versions of the site.

Check out BETRIVERS Sportsbook