USC Trojans at Indiana Hoosiers 2026 Preview: Prediction, Betting Odds & 4 Prop Bets

Big Ten football takes center stage Saturday afternoon when the USC Trojans travel to Bloomington to face the Indiana Hoosiers at Memorial Stadium.

USC enters 7-2 following an impressive 30-18 victory over Ohio State, while Indiana stands at 8-1 after defeating Minnesota 23-16 in overtime.

The Hoosiers enter as 7.5-point favorites in a matchup featuring quarterbacks Josh Hoover or Grant Wilson vs Jayden Maiava, along with explosive offensive weapons Charlie Becker, Nick Marsh and King Miller.

With College Football Playoff implications, this promises to be one of the weekend’s most important conference showdowns.

Game Information

• Matchup: USC Trojans at Indiana Hoosiers
• Date: Saturday, November 14, 2026
• Kickoff: 3:30 PM ET
• TV: CBS
• Venue: Memorial Stadium — Bloomington, Indiana
• Tickets: As low as $268
• Records: USC 7-2 (4-2 Big Ten) | Indiana 8-1 (5-1 Big Ten)
• Point Spread: Indiana -7.5
• Over/Under: 49.5

Indiana must win by at least eight points to cover the 7.5-point spread. USC +7.5 covers with an outright victory or a loss by seven points or fewer.

The 49.5 total requires at least 50 combined points for an over wager to win.

USC: Trojans Looking for Another Statement Victory

USC enters Saturday following an impressive victory over Ohio State, strengthening its postseason ambitions.

Quarterback Jayden Maiava has thrown for 2,525 yards and 20 touchdowns while completing nearly 67% of his passes.

Maiava’s ability to attack defenses vertically has helped USC average 294.6 passing yards and 32.4 points per game.

Wide receiver Trent Mosley delivered five receptions for 101 yards and a touchdown against Ohio State.

Running back King Miller has accumulated 681 rushing yards, providing valuable offensive balance.

The Trojans average 424 total yards per game but face a difficult challenge against Indiana’s outstanding defense.

Defensively, USC allows 24.2 points and 346 yards per game.

The Trojans must protect Maiava, establish Miller early and prevent Indiana from controlling possession.

Indiana: Hoosiers Relying on Defense and Offensive Balance

Indiana enters Saturday riding a two-game winning streak following overtime victories against Michigan and Minnesota.

Quarterback Josh Hoover has thrown for approximately 1,860 yards and 19 touchdowns while committing just two interceptions. The Question is will he be the one starting this game? Grant Wilson deserves the start in my opinion, but if Hoover is healthy there is no way to predict what Cignetti will do.

Running back Turbo Richard leads Indiana’s rushing attack with 745 yards and six touchdowns.

Receiver Charlie Becker has emerged as Hoover’s primary target, accumulating 875 receiving yards and nine touchdowns.

Nick Marsh provides another explosive receiving option.

Indiana averages 32.4 points and nearly 420 total yards per game.

However, the Hoosiers’ defense remains their greatest strength.

Indiana allows just 12.4 points and 259 yards per contest, including only 75.6 rushing yards.

The Hoosiers must maintain that defensive dominance while creating opportunities against USC’s secondary.

Four Prop Bets to Consider

These are suggested betting targets, not verified sportsbook player-prop lines. College player props vary by sportsbook and jurisdiction. Confirm availability, injuries and odds before wagering.

Prop Bet #1: Josh Hoover Over 199.5 Passing Yards

DraftKings

4.5/5

Tip: Hoover Over 199.5 Passing Yards

• 19 Passing Touchdowns
• Only 2 Interceptions
• USC Allows 221 Passing Yards Per Game

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Hoover has demonstrated impressive efficiency throughout the season.

USC allows approximately 221 passing yards per game, creating opportunities for Indiana’s receiving corps.

With Becker and Marsh providing dangerous receiving options, Hoover should generate consistent production.

Prediction: Josh Hoover — 238 passing yards

Prop Bet #2: Charlie Becker Over 79.5 Receiving Yards

FanDuel

4.6/5

Tip: Becker Over 79.5 Receiving Yards

• 875 Season Receiving Yards
• 9 Touchdowns
• Indiana’s Leading Receiver

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Becker remains Hoover’s most dependable receiving weapon.

His ability to create separation and generate explosive gains makes him particularly dangerous against USC’s secondary.

Prediction: Charlie Becker — 96 receiving yards

Prop Bet #3: King Miller Over 54.5 Rushing Yards

Caesars

4.4/5

Tip: Miller Over 54.5 Rushing Yards

• 681 Season Rushing Yards
• USC’s Leading Rusher
• Important Offensive Balance

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Miller faces a difficult matchup against Indiana’s highly ranked rushing defense.

However, USC must establish its running game to prevent Indiana from focusing exclusively on Maiava.

Prediction: King Miller — 62 rushing yards

Prop Bet #4: Jayden Maiava Over 239.5 Passing Yards

BetMGM

4.5/5

Tip: Maiava Over 239.5 Passing Yards

• 2,525 Season Passing Yards
• 20 Touchdowns
• USC Averages 295 Passing Yards

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Maiava leads one of the Big Ten’s most productive passing attacks.

Although Indiana possesses an outstanding secondary, USC may need to throw frequently to remain competitive.

Prediction: Jayden Maiava — 258 passing yards

Players to Watch

Josh Hoover — Indiana: His accuracy and ability to protect the football will determine Indiana’s offensive efficiency.

Charlie Becker — Indiana: Becker’s explosiveness creates difficult coverage assignments for USC.

Jayden Maiava — USC: His passing production and decision-making will be critical against Indiana’s defense.

King Miller — USC: Establishing the rushing attack could help USC control possession and limit Indiana’s defensive pressure.

Keys to the Game

Indiana must establish offensive balance, protect Hoover and prevent Maiava from generating explosive passing plays.

The Hoosiers should pressure USC’s quarterback while exploiting favorable matchups for Becker and Marsh.

USC must protect Maiava, establish Miller and limit Indiana’s rushing attack.

Third-down efficiency, turnovers and red-zone execution could determine the outcome.

Betting Prediction

Indiana -7.5 presents an attractive opportunity considering the Hoosiers’ outstanding defensive production and home-field advantage.

However, USC possesses an explosive passing attack capable of keeping the contest competitive.

The 49.5 total presents another interesting decision.

Both offenses average more than 32 points per game, but Indiana’s defense could limit USC’s scoring opportunities.

Best Bet: Indiana -7.5

The Verdict

USC’s best opportunity comes through Maiava challenging Indiana’s secondary and Miller establishing offensive balance.

However, Indiana possesses the stronger defense and a more balanced offensive attack.

Expect Hoover to connect with Becker on several important plays while Richard provides productive rushing opportunities.

USC remains competitive early, but Indiana’s defensive pressure proves decisive.

The Hoosiers secure another important conference victory and strengthen their College Football Playoff position.

Final Score Prediction

Indiana Hoosiers 31, USC Trojans 20

Picks Summary

Betting Category Pick Best Bet Indiana -7.5 Against the Spread Indiana -7.5 Moneyline Indiana Over/Under Over 49.5 Top Prop Charlie Becker Over 79.5 Receiving Yards

Final Prediction: Indiana 31, USC 20

Indiana wins by 11 points, covering the 7.5-point spread. The projected 51 combined points finish over the 49.5 total.

The Hoosiers improve to 9-1 overall and 6-1 in Big Ten play, while USC falls to 7-3. Indiana strengthens its playoff résumé with a statement victory in Bloomington.