Nebraska defeated Illinois 20-7 last season on the road, holding Illinois to only 21 rushing yards. Illinois currently boasts an 8+ turnover ratio while Nebraska freshman quarterback Dylan Raiola (73.84% completion rate, one interception in three starts) should pull away without turning over the ball; Bret Bielema is 9-3 against the spread when betting as an underdog road team; therefore this requires betting against the trend.
Prediction: Nebraska 27 Illinois 17
DraftKings
4.6/5
Tip: Bet Nebraska -8.5
Two much improved teams
Raiola will be the difference
Nebraska at home
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NC State at No. 21 Clemson
Point Spread: Clemson -19.5
Moneyline NC State +800
Moneyline Clemson -1400
Over/Under 47.5
NC State quarterback Grayson McCall has an unspecified injury, so this line may change depending on his status for Saturday’s matchup against Clemson. Each of the last three games in this series has been decided by 10 or fewer points; NC State won 24-17 last season in Clemson but hasn’t triumphed there since 2002 due to quarterback issues that will make this tough for NC State to overcome with Clemson having just come off a bye week.
Prediction: Clemson 31 NC State 17
DraftKings
4.6/5
Tip: Bet NC State +19.5
Clemson coming off bye week
McCall is questionable
Clemson at home
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Marshall at No. 3 Ohio State
Point Spread: Ohio State -39.5
Moneyline Marshall
Moneyline Ohio State
Over/Under 51.5
Ohio State had its bye week and has yet to allow an offensive touchdown this season, thanks to Will Howard’s efficient play and two running backs who average over 7.0 yards per carry (TreVeyon Henderson and Quinshon Judkins) will prove difficult for opponents to stop. Marshall averages 6.6 yards per rush attempt but Ohio State is different from the other Marshall opponents.
Prediction: Ohio State 52 Marshall 10
DraftKings
4.6/5
Tip: Bet Ohio State -39.5
Buckeyes defense dominates
Marshall will struggle to throw
Ohio State at home
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Arkansas State at No. 20 Iowa State
Point Spread: Iowa State -21.5
Moneyline Arkansas St +1060
Moneyline Iowa State -2300
Over/Under 51.5
Iowa State had an extra week off before facing Arkansas State, who challenged Michigan hard before succumbing 28-18. Arkansas State struggled against running plays so this should be an opportunity for Cyclones running back Abu Sama to shine against an Arkansas State defense that is susceptible to run plays. Iowa State lost to Ohio in 2023 so Matt Campbell won’t take this Group 5 school lightly, so this shouldn’t feel like an easy win.
Prediction: Iowa State 30 Arkansas State 17
DraftKings
4.6/5
Tip: Bet Arkansas State +21.5
Sama to shine
Iowa State too talented
Iowa State at home
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Miami, Ohio at No. 17 Notre Dame
Point Spread: Notre Dame -27.5
Moneyline Miami of Ohio +3000
Moneyline Notre Dame -10000
Over/Under 43.5
Notre Dame knows its task now. After losing to Northern Illinois in Week 2, they must now use their superior offense to win every game going forward. After managing 11 points per game against Northwestern and Cincinnati combined, and giving up 182.5 rushing yards per game on 5.6 yards per carry in their first two games the Redhawks will find themselves behind quickly in this game.
Prediction: Notre Dame 45 Miami of Ohio 13
DraftKings
4.6/5
Tip: Bet Notre Dame -27.5
Leonard to shine
Irish too talented
Irish at home
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Buffalo at No. 23 Northern Illinois
Point Spread: Northern Illinois -13.5
Moneyline Buffalo +460
Moneyline Northern Illinois -650
Over/Under 43.5
Northern Illinois was given an extra week off after its impressive win against Notre Dame, and expectations will only increase under coach Thomas Hammock. Ethan Hampton has excelled so far with mistake-free play (526 yards, six touchdowns and no interceptions). Meanwhile, Buffalo is improving under first-year coach Pete Lembo; their Bulls average just one turnover per game; these teams last met each other back in 2021.
Prediction: Northern Illinois 33 Buffalo 17
DraftKings
4.6/5
Tip: Bet Northern Illinois -13.5
Hampton to play well
Northern Illinois too talented
Northern Illinois at home
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Kent State at No. 10 Penn State
Point Spread: Penn State -48.5
Moneyline Kent State +460
Moneyline Penn State -650
Over/Under 55.5
Kent State lost 71-0 to Tennessee and now must face Penn State, which is coming off a bye week after an underwhelming performance against Bowling Green in Week 2. Penn State will rely heavily on its rushing attack, led by Nick Singleton and Kayton Allen, who both average seven yards per carry combined.
Prediction: Penn State 58 Kent State 7
DraftKings
4.6/5
Tip: Bet Penn State -48.5
Penn State rolls on the ground
Penn State too talented
Penn State at home
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No. 11 USC (-6) at No. 18 Michigan
Point Spread: USC -5.5
Moneyline USC -230
Moneyline Michigan +188
Over/Under 45.5
This line has seen its spread decrease by half-point at other sportsbooks, but giving home team points in any matchup between ranked teams can be risky. USC has established itself with Miller Moss at quarterback and only committed one turnover through three weeks – provided Michigan doesn’t exert pressure early in the game. Meanwhile, Michigan has an uncertain quarterback situation between Davis Warren and Alex Orji with an unfavorable turnover ratio, giving up four turnovers over that span, which won’t bode well against USC’s run defense.
Prediction: USC 31 Michigan 17
DraftKings
4.6/5
Tip: Bet Penn State USC -5.5
Moss to play well
Michigan offense to struggle
Michigan at home
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Georgia Tech at No. 19 Louisville
Point Spread: Louisville -10.5
Moneyline Georgia Tech +310
Moneyline USC -400
Over/Under 57.5
Here is an excellent matchup: Louisville beat Georgia Tech 39-34 last season and boasts a 263-yard-per-game rushing attack. The passing game under Tyler Shough, who ranks third in the ACC with a 188.4 passer rating has been solid. In response, Haynes King leads Georgia Tech’s relentless running game as their frontline defense. Although this line seems high at first, Louisville’s record as an underdog under Brohm stands out at 7-2 against the spread at home and 6-2 as an away favorite ATS.
Prediction: Louisville 27 Georgia Tech 24
DraftKings
4.6/5
Tip: Bet Georgia Tech +10.5
The run game will dominate
Shough will be the difference
Louisville at home
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UCLA at No. 16 LSU
Point Spread: LSU -24.5
Moneyline UCLA +1400
Moneyline LSU-4000
Over/Under 55.5
UCLA quarterback Ethan Garbers boasts a 54.1% completion percentage, with his Bruins averaging an average 3.5 yards per carry, which makes for an inevitability against LSU at Death Valley. With LSU coming off an emotional victory at South Carolina and knowing they have 9-2 record as home favorites under Brian Kelly.
Prediction: LSU 48 UCLA 13
DraftKings
4.6/5
Tip: Bet LSU -24.5
LSU to dominate
UCLA defense is bad
LSU at home
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No. 12 Utah at No. 14 Oklahoma State
Point Spread: Utah -1.5
Moneyline Utah -118
Moneyline Oklahoma St -102
Over/Under 52.5
This Big 12 matchup promises to be exciting. Utah turned to quarterback Isaac Wilson last week and relies on Micah Bernard and Mike Mitchell’s no-nonsense running attack for an effective run game, while Oklahoma State has struggled running the football but veteran quarterback Alan Bowman averages 322.3 passing yards per game with no interceptions this season. As road underdogs since last season, Utah is just 1-3 against S/U but has gone 2-2 ATS as an underdog while the Cowboys are 5-1 but 2-4 in terms of home favoritism – truly making this an interesting matchup!
Prediction: Oklahoma State 27 Utah 24
DraftKings
4.6/5
Tip: Bet Oklahoma State +1.5
Bowman to have a huge game
Utah will need to pass to win
Oklahoma State at home
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South Florida at No. 8 Miami, Fla
Point Spread: Miami -16.5
Moneyline South Florida +550
Moneyline Miami -820
Over/Under 65.5
Miami leads the FBS in yards per play and Cam Ward is among those contending for the Heisman Trophy. South Florida played Alabama in Week 2, and Alex Golesh will likely vie for Power 4 vacancies this off-season. Under Golesh’s watch as an underdog manager, South Florida went 7-2 against them against Miami (ATS record of 7-2 under him against Hurricanes); however, Miami boasts one of the strongest third-down defenses in FBS; making it hard for South Florida to keep up in second half.
Prediction: Miami 44 South Florida 23
DraftKings
4.6/5
Tip: Bet Miami -16.5
Ward to dominate
South Florida will hang tough for awhile
Miami at home
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Vanderbilt at No. 7 Missouri
Point Spread: Missouri -21.5
Moneyline Vanderbilt +890
Moneyline Missouri -1700
Over/Under 52.5
The Tigers have won three consecutive matches between these teams, and Vanderbilt has been an intriguing team this year. They led Diego Paiva’s upset against Virginia Tech before losing in overtime against Georgia State in Week 3. However, Vanderbilt only committed one turnover this season, which might allow them to remain competitive during the SEC opener.
Prediction: Missouri 34 Vanderbilt 16
DraftKings
4.6/5
Tip: Bet Vandy +21.5
Tigers are hot
Vandy inconsistent
Missouri at home
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No. 13 Kansas State at BYU
Point Spread: Kansas State -7.5
Moneyline Kansas State -260
Moneyline BYU +210
Over/Under 47.5
Late-night battle between unbeaten Big 12 teams. BYU boasts two road victories and quarterback Jake Retzlaff is both the passing and rushing leader for BYU; their defense allows just 3.4 yards per carry against Kansas State’s physical running game that averages 244.3 yards on seven yards per carry!
Prediction: BYU 26 Kansas State 24
DraftKings
4.6/5
Tip: Bet BYU +7.5
Retzlaff to have big game
BYU at home
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UL-Monroe at No. 1 Texas
Point Spread: Texas -44.5
Moneyline UL-Moroe
Moneyline Texas
Over/Under 52.5
Manning averaged 22.7 yards per completion when taking over for Quinn Ewers last week and may lean heavily on a running game that averages 173.3 yards per game to beat Bryant Vincent’s Warhawks, who have gone unbeaten under first-year coach Bryant Vincent so far this season. Last year the Longhorns beat UL-Monroe 52-10 under Manning who is off to an incredible start this year!
Prediction: Texas 55 UL-Monroe 6
DraftKings
4.6/5
Tip: Bet Texas -44.5
Manning to have big game
Texas at home
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No. 6 Tennessee at No. 15 Oklahoma
Point Spread: Tennessee -6.5
Moneyline Tennessee -260
Moneyline Oklahoma +210
Over/Under 57.5
This game presents another difficult decision. Oklahoma is making its SEC debut and has seen its line reduce by half a point from its initial opening price. Oklahoma quarterback Jackson Arnold and Tennessee’s Nico Iamaleava will both be under intense scrutiny here; Arnold has been sacked nine times while Iamaleava has three. If Tennessee can avoid turnovers and use Dylan Sampson to start running upfield then that could ruin Oklahoma’s party.
Prediction: Tennessee 37 Oklahoma 24
DraftKings
4.6/5
Tip: Bet Tennessee -6.5
Nico Iamaleava dominates
Sooners must force turnovers
Oklahoma at home
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GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-522-4700, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD). 21+ and present in most states. (18+ DC/KY/NH/WY). Void in ONT/OR/NH. Eligibility restrictions apply. On behalf of Boot Hill Casino & Resort (KS). Pass-thru of per wager tax may apply in IL. 1 per new customer. Must register new account to receive reward Token. Must select Token BEFORE placing min. $5 bet to receive $300 in Bonus Bets if your bet wins. Min. -500 odds req. Token and Bonus Bets are single-use and non-withdrawable. Bet must settle by and Token expires 2/22/26. Bonus Bets expire in 7 days (168 hours). Stake removed from payout. Terms: sportsbook.draftkings.com/promos. Ends 2/15/26 at 11:59 PM ET. Sponsored by DK.
Bowling Green at No. 25 Texas A&M
Point Spread: Texas A&M -22.5
Moneyline Bowling Green +1000
Moneyline Texas A&M -2100
Over/Under 52.5
Texas A&M is back in the AP Top 25 thanks to Marcel Reed, who proved a formidable dual-threat playmaker against Florida with 178 passing yards, 83 rushing yards, and three total touchdowns. Texas A&M also features two running backs who average more than five yards per carry in Le’Veon Moss and Amari Daniels respectively. Bowling Green had an extra week off to prepare after giving Penn State fits
Prediction: Texas A&M 31 Bowling Green 20
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Falcons to stay in the game until late
Falcons must force turnovers
Texas A&M at home
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Georgia Southern at No. 5 Ole Miss
Point Spread: Ole Miss -36.5
Moneyline Georgia Southern
Moneyline Ole Miss
Over/Under 66.5
Lane Kiffin and Clay Helton will square off in an epic battle of former USC coaches, featuring JC French’s Eagles scoring an average of 35.7 points per game compared to 29 points allowed per game by Georgia Southern against Ole Miss’ 692 yards per game FBS offense that hasn’t allowed a touchdown yet! Expect Ole Miss to extend its winning streak ATS by outlasting another massive line with ease.
Prediction: Ole Miss 61 Georgia Southern 13
DraftKings
4.6/5
Tip: Bet Ole Miss -36.5
Over early
Rebels offense explosion
Ole Miss at home
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Gambling Problem? Call 1-800-GAMBLER or visit RG-help.com. Call 1-888-789-7777 or visit ccpg.org/chat (CT). Hope is here. Visit www.helpmygamblingproblem.org (MA). Play it Safe. Call 1-800-547-6133 or visit mdgamblinghelp.org (MD). Call 1-855-860-2942 or visit gamblinghelplineonline.org (WV). 21+ (18+ DC, KY, MD and restricted states for KS). An affiliation with Kansas Star Casino. First online real money wager only. $5 free deposit credited. Bonus credited upon wager of $5 or more within 72 days after receipt. Restrictions apply. See terms at sportsbook.fanduel.com.
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