Seen on:
as known from New York Timesas known from USA Todayas known from yahoo!
OH
The Grueling Truth - Where Legends Speak / Latest College Football News & Rumors / College football picks, predictions against the spread for Week 8 all of the top 25 games

College football picks, predictions against the spread for Week 8 all of the top 25 games

Publish Date: 10/21/2022
Fact checked by: Mark Lewis

Week 8

So far this season ats we are 46-33, and as we head down the stretch, the games will only get bigger. Check out the top football odds.

Iowa at No. 2 Ohio State (-29) (noon, FOX)

This is an intriguing matchup as the Hawkeyes only give up 9 points per game, while Ohio State averages over 48 points per game. Iowa’s issue is their offense is horrid and that lack of offense will lead to a defense that gets tired and eventually breaks.

Prediction: Ohio State 45  Iowa 9(Take the Buckeyes and give the points)

Check out the top sportsbooks for betting on college football

FanDuel
4.6/5
FanDuel Review
New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days
Bet now
Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET. Call 1-888-789-7777 or visit ccpg.org/chat (CT). Hope is here. GamblingHelplineMA.org or call (800) 327-5050 for 24/7 support (MA). Visit www.mdgamblinghelp.org (MD). Call 1-877-HOPENY or text HOPENY (467369) (NY). 21+ (18+ DC, IA, KY, WV) only. New users only or text HOPENY (467369) (NY). Casino, First online real money wager only. $5 first deposit required. Min $5 wager required for 5 consecutive days. Bonus issued as non-withdrawable Bet Reset tokens. Refund from token issued as nonwithdrawable bonus bet that expire 7 days after receipt. Max refund $200 per day. Restrictions apply, including token expiration. See full terms at fanduel.com/sportsbook. Call 1-877-770-7867 (LA).
BetMGM
4.5/5
BetMGM Review
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Bet now
Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.
DraftKings
4.5/5
DraftKings Review
New DraftKings Customers: Spend $5+ Get $150 in Bonus Bets *Paid Within 14 Days
Bet now
GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). 21+ and present in most states. (18+ DC/NH/PR/WY). Void in CAN. Eligibility restrictions apply. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL. 1 per new DraftKings customer. $5+ first-time bet req. Max. $150 issued as non-withdrawable Bonus Bets that expire in 7 days after issuance. Stake removed from payout. Reward issued as $50 in Bonus Bets every 7 days via click-to-claim for 14 days. 7 days = 168hrs. Terms: sportsbook.draftkings.com/promos. Ends 8/23/26 at 11:59 PM ET. Sponsored by DK.

No. 14 Syracuse at No. 5 Clemson (-12.5) (noon, ABC) 

Syracuse has a balanced offensive attack and an excellent defense. They are a very good football team. Will they win? Probably not, but 12 points is a huge spread in this one, as I expect Syracuse to give Clemson all they can handle. Syracuse is 5-1 ats this season.

Prediction: Clemson 27  Syracuse 24(Take the Orangemen and the points)

Check out the top odds for betting on Syracuse/Clemson

No. 21 Cincinnati (-3) at SMU (noon, TBD) 

Cincinnati is coming off a bye after two tougher-than-expected wins, SMU has an excellent passing attack, and the Bearcats will have their hands full.

Prediction: Cincinnati 31  SMU 27(Take the Bearcats to cover)

No. 20 Texas (-4.5) at No. 11 Oklahoma State (3:30 p.m., ABC) 

The Longhorns are a different team with Quinn Ewers under center and the Cowboys are coming off of their first loss of the season. The last five games between these teams have been decided by less than a touchdown.

Prediction: Oklahoma State 34  Texas 31(Take the Cowboys and the points)

No. 7 Ole Miss (Pick ’em) at LSU (3:30 p.m., CBS) 

The Rebels average over 271 yards per game on the ground and should give LSU all they can handle. I think the Tigers play this game closer than they did against Tennessee.

Prediction: Ole Miss 37  LSU 27(Take the Rebels to win)

Memphis at No. 25 Tulane (-7) (3:30 p.m., ESPN2) 

Seven points seem like a lot to cover in this one, as Memphis is a solid team. Tulane if they keep rolling could be a New Years’ six-team, how will they handle this, will they be too happy or will they continue to play well?

Prediction: Tulane 31  Memphis 21(Take Tulane and give the points)

No. 9 UCLA at No. 10 Oregon (-6) (3:30 p.m., FOX)

This should be a classic high-scoring affair as both teams average over 40 points per game. After getting thumped in their season opener the Ducks have rebounded and the Bruins are still undefeated and a win here will push them even closer to a CFP position.

Prediction: UCLA 44  Oregon 41(Take the Bruins and the points)

Check out the best odds for Oregon/UCLA

Boston College at No. 13 Wake Forest (-20.5) (3:30 p.m., ACC Network)

Last year the Demon Deacons won this matchup 41-10, and not much has changed since that meeting.

Prediction: Wake Forest 45  Boston College 13(Take Wake and give the points)

No. 24 Mississippi State at No. 6 Alabama (-21) (7 p.m., ESPN) 

Mississippi State is led by QB Will Rogers, and they are dangerous, but Alabama is coming off a loss, and Bryce Young will light up the night sky!

Prediction Alabama 52  Mississippi State 21(Take the Tide and give the points)

Minnesota at No. 16 Penn State (-4) (7:30 p.m., ABC) 

The Gophers are only averaging 12 points over their last two contests, and they are sinking fast. Penn State got beat down in Ann Arbor. Look for a Nittany Lions bounce-back win. Check out the top football betting sites.

Prediction: Penn State 31  Minnesota 16(Take the Lions and give the points)

No. 17 Kansas State at No. 8 TCU (-5) (8 p.m., FOX) 

TCU will be looking for their third straight win over a ranked opponent. The Wildcats come in averaging over 244 yards per game on the ground.

Prediction: TCU 38  Kansas State 31(Take the Frogs and give the points)

Read Also
College Football Week 8 Predictions: Ole Miss/Geo, Ala/Tenn, LSU/Vandy, ND/USC
  Week 7 saw quality wins by Indiana, USC, Alabama, Texas, A&M, ...
Diego Pacheco vs. Steven Nelson This Saturday on DAZN
Rising contender Diego Pacheco continues to make his journey up the super ...
BetMGM Promo
College Football Rivalry Week Predictions: OSU/Mich, Tex/Tex A&M, So.Car/Clem, and More
Week 13 gave us thrilling upsets, with three two-loss SEC teams losing ...
NCAA Football Week 12: Betting All Top 25 Games against the Spread
Point Spread: Texas -13.5 Moneyline Texas -610 Moneyline Arkansas +440 Over/Under 56.5 ...
NCAA Football Week 11: Betting All Top 25 Games against the Spread
week one Against the spread: 8-8 Week Two Against the Spread 9-7 ...
NCAA Football Week 10: Betting All Top 25 Games against the Spread
week one Against the spread: 8-8 Week Two Against the Spread 9-7 ...
NCAA Football Week 9: Betting All Top 25 Games against the Spread
week one Against the spread: 8-8 Week Two Against the Spread 9-7 ...
College Football Week 8 Predictions: Tex/Geo, Ala/Tenn, Mich/ILL, LSU/Ark and more
Week 7 was another amazing chapter in one of the better regular ...
NCAA Football Week 8: Betting All Top 25 Games against the Spread
week one Against the spread: 8-8 Week Two Against the Spread 9-7 ...
College Football Week 7 Predictions: OSU/Oregon, OKL/Tex, Penn.St/USC, Ole Miss/LSU and More
In week 6, all hell broke loose with Vandy in a complete ...
Top Betting Sites
Top Betting Bonuses
FanDuel
4.6/5
BetMGM
4.5/5
DraftKings
4.5/5
Fanatics
4.2/5
4.4/5
4.5/5
FanDuel
FanDuel Promo
New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days
T&Cs apply
4.6/5
Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET. Call 1-888-789-7777 or visit ccpg.org/chat (CT). Hope is here. GamblingHelplineMA.org or call (800) 327-5050 for 24/7 support (MA). Visit www.mdgamblinghelp.org (MD). Call 1-877-HOPENY or text HOPENY (467369) (NY). 21+ (18+ DC, IA, KY, WV) only. New users only or text HOPENY (467369) (NY). Casino, First online real money wager only. $5 first deposit required. Min $5 wager required for 5 consecutive days. Bonus issued as non-withdrawable Bet Reset tokens. Refund from token issued as nonwithdrawable bonus bet that expire 7 days after receipt. Max refund $200 per day. Restrictions apply, including token expiration. See full terms at fanduel.com/sportsbook. Call 1-877-770-7867 (LA).
BetMGM
BetMGM Promo
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
T&Cs apply
4.5/5
Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.
DraftKings
DraftKings Promo
New DraftKings Customers: Spend $5+ Get $150 in Bonus Bets *Paid Within 14 Days
T&Cs apply
4.5/5
GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). 21+ and present in most states. (18+ DC/NH/PR/WY). Void in CAN. Eligibility restrictions apply. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL. 1 per new DraftKings customer. $5+ first-time bet req. Max. $150 issued as non-withdrawable Bonus Bets that expire in 7 days after issuance. Stake removed from payout. Reward issued as $50 in Bonus Bets every 7 days via click-to-claim for 14 days. 7 days = 168hrs. Terms: sportsbook.draftkings.com/promos. Ends 8/23/26 at 11:59 PM ET. Sponsored by DK.
Fanatics
Fanatics Promo
10 x $100 bet match in FanCash
T&Cs apply
4.2/5
Must be 21+. GAMBLING PROBLEM? CALL 1-800-GAMBLER OR CALL 1-800-MY-RESET, www.mdgamblinghelp.org (MD), (800)-327-5050 or gamblinghelplinema.org (MA), Call (877)8-HOPENY or text HOPENY (467369) (NY), (888) 789-7777 or ccpg.org (CT), morethanagame.nc.gov (NC), 1800gambler.net (WV)
Caesars Promo
Bet $1 and get double the winnings up to $25 for your next 10 bets
T&Cs apply
4.4/5
21+ New users only. Must register using eligible promo code. First bet after registration must qualify. Max. Bonus Bet: $1,000. Bonus Bet expires 14 days after receipt. Void where prohibited. See Caesars.com/promos for full terms. Gambling Problem? 1-800-GAMBLER (1-800-426-2537)
Latest Sport News
Ranking the Top 10 Big Ten Wide Receivers Heading Into the 2026 Season
The Big Ten enters the 2026 college football ...
Indiana Football, Not the New York Knicks, Deserved the ESPY for Best Team
The New York Knicks authored a tremendous championship ...
Xavier Men’s Basketball to Participate in Outdoor Exhibition Doubleheader Fea...
CINCINNATI — The Xavier Musketeers men’s basketball team ...
WNBA Connecticut Sun vs Indiana Fever: Game Preview and Prediction
Date: Friday, July 17, 2026Time: 8:00 PM ET ...
Spain Beat Argentina in Extra Time to Win the 2026 FIFA World Cup
For 106 minutes, the 2026 World Cup final ...
Indianapolis Colts 2026 Quarterback Preview: Can Daniel Jones Hold Off Anthon...
The Indianapolis Colts enter the 2026 season with ...
Montrezl Harrell’s 35 Points Power The Ville to Dominant Game 2 Victory...
The Louisville Alumni (The Ville) responded in emphatic ...
Ranking the Top 10 Big Ten Running Backs Heading Into the 2026 Season
The Big Ten lost several outstanding running backs ...
Our Team
Mike GoodpasterJames ErnestMark LewisAuthor IconJohn Raspanti
+8
Mike Goodpaster
Mike Goodpaster
Chief Editor
James Ernest
James Ernest
Author
Mark Lewis
Mark Lewis
Editor
Author Icon
Christopher Carlson
Author
John Raspanti
John Raspanti
Author
Samuel Teets
Samuel Teets
US Sports Veteran
Daniel Kornhauser
Daniel Kornhauser
Author
Ellis Williams
Ellis Williams
Author
Chris Benedict
Chris Benedict
Editor
Shelley Harcar
Shelley Harcar
Sports Writer
Marvin Uzor
Marvin Uzor
Author
Dr. Jay Gee
Dr. Jay Gee
Author
LaMarr Fields
LaMarr Fields
Author

21+ and present in OH. Gambling Problem? Call 1-800-GAMBLER.

This site is using Cloudflare and adheres to the Google Safe Browsing Program. We adapted Google's Privacy Guidelines to keep your data safe at all times.
CloudflareSSL
Close
Ready to Win Big? Join the Elite with Our Sports Betting Deals!
FanDuel
FanDuel Promo
New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days
Our Favorite
T&Cs and 21+ apply
Code:
Open FanDuel
Get Bonus
BetMGM
BetMGM Promo
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Best Slots
T&Cs and 21+ apply
Code:
Open BetMGM
Get Bonus
DraftKings
DraftKings Promo
New DraftKings Customers: Spend $5+ Get $150 in Bonus Bets *Paid Within 14 Days
Newcomer
T&Cs and 21+ apply
Code:
Open DraftKings
Get Bonus
Find out what the legends have to say about sports this week....
×
Your Promo Code:
The bonus offer of was already opened in an additional window. If not, you can open it also by clicking the following link:
Play now