NBA Playoffs Game 2 Indiana Pacers vs Cleveland Cavaliers: Odds, Tips and Predictions 05-06-25

​The Cleveland Cavaliers will host the Indiana Pacers in Game 2 of their Eastern Conference Semifinals series on Tuesday, May 6, 2025, at 7:00 PM ET. The Pacers lead the series 1-0 after a commanding 121-112 victory in Game 1. Despite being the top seed in the East, the Cavaliers are under pressure to bounce back and even the series.​

Indiana Pacers vs Cleveland Cavaliers

• Point Spread: Cavaliers -10
• Moneyline Pacers +385
• Moneyline Cavaliers -500
• Over/Under 208.5

Cleveland is favored to win Game 2, but Indiana’s recent performance suggests they could cover the spread. The Pacers have won four of their last five meetings with the Cavaliers, including Game 1. The over/under line reflects both teams’ high-scoring capabilities.​

🔍 Game 1 Recap: Pacers Dominate from Deep

In Game 1, the Pacers’ three-point shooting was the difference-maker. They shot 52.8% from beyond the arc, while the Cavaliers struggled at 23.7%. Donovan Mitchell, Cleveland’s star guard, went 1-for-11 from three-point range, despite scoring efficiently inside the arc. The absence of Darius Garland due to a toe injury was felt, as the Cavaliers’ offense lacked its usual fluidity. Defensively, Cleveland’s over-helping left Indiana’s shooters with open looks, contributing to the blowout loss.

Indiana vs Cleveland Moneyline

Moneyline value exists for a bet on the Pacers. I am leaning towards taking the Pacers and the points. To find the best line, you need accounts with multiple sportsbooks, and we got you covered as we break down the best sports betting app

DraftKings

4.5/5

Tip: Bet Pacers +10

• Rebounds to be key
• Turnovers to be key
• Cavs at Home

New DraftKings Customer Offer: SPEND $5, GET $200 IN BONUSES

Get bonus now

🔑 Key Matchups & Strategies

Cleveland Cavaliers

• Offensive Adjustments: The Cavaliers need to improve their three-point shooting to match their regular-season average of 39.9%, which led the league. Utilizing pick-and-rolls and off-ball movement can exploit Indiana’s drop coverage defense. ​

• Defensive Focus: Containing Tyrese Haliburton is crucial. Haliburton’s playmaking ability can dismantle defenses, so the Cavaliers must disrupt his rhythm and force him into a scoring role, which is less natural for him.

Indiana Pacers

• Continued Perimeter Success: The Pacers should continue to capitalize on their three-point shooting, which was a significant factor in Game 1.

• Defensive Consistency: Maintaining their improved defense, which has risen from 24th to 13th in the league, will be key to limiting Cleveland’s offensive threats. ​

The best NBA betting sites

To satisfy the ever-growing market of NBA bettors, the best basketball sportsbooks offer unique user experiences, huge payouts, and fantastic bonuses. Gamers no longer have to go to casinos to find some physical action. Online bookies let you play the game of risk from the comfort of your own home. We hope our guide can point you in the right direction so you can find the best gambling experiences on the internet.

Best Brand

FanDuel Promo

New Users – Get $350 in Bonus Bets when you wager $5 for 7 days

Get bonus now

Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET. Call 1-888-789-7777 or visit ccpg.org/chat (CT). Hope is here. GamblingHelpLineMA.org or call (800) 327-5050 for 24/7 support (MA). Visit www.mdgamblinghelp.org (MD). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY). 21+ (18+ D.C., KY, WY) and present in select states (for KS, in affiliation with Kansas Star Casino). First online real money wager only. Min $5 wager required for 7 consecutive days.$5 first deposit required. Bonus issued as nonwithdrawable bonus bets which expire 7 days after receipt. Restrictions apply. See terms at sportsbook.fanduel.com. Call 1-877-770-7867 (LA). ™/© 2026 MLB

Best Slots

BetMGM Promo

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Get bonus now

Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.

Newcomer

DraftKings Promo

New DraftKings Customer Offer: SPEND $5, GET $200 IN BONUSES

Get bonus now

To be eligible for DraftKings Sportsbook and the Promotion, you must be physically located in AR, AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA (select parishes), MA, MD, ME, MI, MO, NC, NJ, NH, NY, OH, OR, PA, PR (residents only), TN, VA, VT, WY, WV, CA-ONT or CA-AB (each an “Eligible Jurisdiction” or, collectively, the “Eligible Jurisdictions”). Must be 21+ years of age or older (18+ if in DC/NH/PR/WY/CA-AB) (19+ in CA-ONT). GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA) Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). 21+ and present in most states. (18+ DC/NH/PR/WY). Void in CAN. Eligibility restrictions apply. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL. 1 per new DraftKings customer. $5+ first-time bet req. Max. $200 issued as non-withdrawable Bonus Bets. Stake removed from payout. Reward issued as $50 in Bonus Bets every 7 days via click-to-claim for 21 days. Bonus Bets and click-to-claims expire 7 days (168hrs) after issuance. Terms: Promos | DraftKings Sportsbook . Ends 9/20/26 at 11:59 PM ET. Sponsored by DK.

Award

Fanatics Promo

10 x $100 bet match in FanCash

Get bonus now

Must be 21+. GAMBLING PROBLEM? CALL 1-800-GAMBLER OR CALL 1-800-MY-RESET, www.mdgamblinghelp.org (MD), (800)-327-5050 or gamblinghelplinema.org (MA), Call (877)8-HOPENY or text HOPENY (467369) (NY), (888) 789-7777 or ccpg.org (CT), morethanagame.nc.gov (NC), 1800gambler.net (WV)

Indiana vs Cleveland Over/Under Analysis

I will bet this game on the over, I expect a lot of points out of Minnesota.

DraftKings

4.5/5

Tip: Bet the Over 208.5

• Siakham Big Night
• Mitchell Big Night
• Cavs at Home

New DraftKings Customer Offer: SPEND $5, GET $200 IN BONUSES

Get bonus now

I expect the Cavs to bounce back at home in game 2, but 10 points id too much to give to a Pacers team that I feel will win this series.

Bet Pacers +10