No. 10 Louisville Cardinals at Memphis Tigers 2026 Preview: Prediction, Betting Outlook & 4 Prop Bets

College basketball takes center stage Sunday afternoon when the No. 10 Louisville Cardinals travel to Memphis to face the Tigers at FedExForum.

Louisville enters 2-0 following an impressive 107-57 victory over Morehead State, while Memphis stands at 2-1 after suffering a 105-81 defeat against No. 22 Vanderbilt.

The Cardinals enter as an early favorite based on their dominant performances behind Flory Bidunga, Jackson Shelstad, Seth Trimble and Adrian Wooley. Memphis counters with explosive guard Jayden Reid, Luke Almodovar and Rihards Vavers.

With Louisville looking to remain undefeated and Memphis attempting to secure another nationally significant victory, Sunday’s matchup promises an entertaining nonconference showdown.

Game Information

• Matchup: No. 10 Louisville Cardinals at Memphis Tigers
• Date: Sunday, November 15, 2026
• Tipoff: 1:00 PM ET (12:00 PM CT)
• TV: ESPN
• Venue: FedExForum — Memphis, Tennessee
• Tickets: As low as $34
• Records: Louisville 2-0 | Memphis 2-1
• Point Spread: Not yet confirmed
• Over/Under: Not yet confirmed

Louisville enters with significant advantages in rebounding, depth and defensive efficiency. However, Memphis possesses home-court advantage and an offense capable of producing explosive scoring runs.

Louisville: Cardinals Looking to Remain Undefeated

Louisville enters Sunday following victories over Chattanooga and Morehead State.

Head coach Pat Kelsey’s Cardinals have averaged an impressive 95.5 points while allowing just 63.5 through their opening two contests.

Guard Adrian Wooley leads Louisville with 13.5 points per game.

Forward Flory Bidunga has emerged as a dominant interior presence, averaging 13 points and eight rebounds while shooting 75% from the field.

Obinna Ekezie Jr. provides additional frontcourt production with 12.5 points and 6.5 rebounds per contest.

Seth Trimble averages 12 points, while Karter Knox adds another 12 points and a team-leading 8.5 rebounds.

Point guard Jackson Shelstad contributes 10.5 points and four assists per game, providing valuable offensive leadership.

Louisville averages 50.5 rebounds and 19 assists, demonstrating outstanding offensive balance.

The Cardinals must control the boards, limit turnovers and exploit Memphis’ defensive vulnerabilities.

Memphis: Tigers Looking for Statement Victory

Memphis enters Sunday attempting to rebound from a difficult road loss against Vanderbilt.

Head coach Penny Hardaway’s Tigers opened the season with impressive victories over Iowa State and VCU.

Guard Jayden Reid has emerged as Memphis’ most explosive offensive weapon, scoring 58 points across his first two games.

Reid earned national recognition for his early performances, although an ankle injury sustained against Vanderbilt creates uncertainty surrounding his availability.

Rihards Vavers provides another important scoring option, averaging 16 points through the opening two games.

Luke Almodovar contributed a season-high 21 points against Vanderbilt but also exited that contest following a hard fall.

Tylik Weeks provides additional offensive support, giving Memphis multiple perimeter scoring options.

Memphis averages 83.3 points through three games but allows approximately 89.7.

The Tigers must improve their defensive consistency, protect the basketball and prevent Louisville from dominating the rebounding battle.

Four Prop Bets to Consider

These are suggested player-prop targets, not verified sportsbook lines. College basketball props vary by sportsbook and jurisdiction. Confirm player availability, current odds and lines before wagering.

Prop Bet #1: Flory Bidunga Over 7.5 Rebounds

DraftKings

4.5/5

Tip: Bidunga Over 7.5 Rebounds

• 8.0 Rebounds Per Game
• 75% Field Goal Shooting
• Louisville Interior Presence

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Bidunga provides Louisville with a significant advantage around the basket.

Memphis has struggled defensively, creating opportunities for Louisville to generate second-chance possessions.

Prediction: Flory Bidunga — 10 rebounds

Prop Bet #2: Jackson Shelstad Over 4.5 Assists

FanDuel

4.6/5

Tip: Shelstad Over 4.5 Assists

• 4 Assists Per Game
• Louisville Averages 19 Assists
• Experienced Point Guard

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Shelstad remains an important offensive facilitator for Louisville.

His ability to create opportunities for Bidunga, Trimble and Wooley should generate productive passing numbers.

Prediction: Jackson Shelstad — 6 assists

Prop Bet #3: Adrian Wooley Over 12.5 Points

Caesars

4.4/5

Tip: Wooley Over 12.5 Points

• 13.5 Points Per Game
• 52.6% Field Goal Shooting
• Louisville Leading Scorer

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Wooley has demonstrated impressive scoring efficiency early in the season.

Memphis’ defensive struggles could create favorable opportunities for Louisville’s perimeter attack.

Prediction: Adrian Wooley — 17 points

Prop Bet #4: Rihards Vavers Over 13.5 Points

BetMGM

4.5/5

Tip: Vavers Over 13.5 Points

• 16 Points Per Game Through Two Games
• 52.9% Shooting
• Important Memphis Scoring Option

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Vavers has provided dependable offensive production for Memphis.

With uncertainty surrounding Reid and Almodovar, Vavers could receive additional scoring opportunities.

Prediction: Rihards Vavers — 18 points

Players to Watch

Flory Bidunga — Louisville: His rebounding, interior scoring and rim protection could determine Louisville’s advantage inside.

Jackson Shelstad — Louisville: His playmaking and decision-making will be critical against Memphis’ defensive pressure.

Jayden Reid — Memphis: His explosive scoring could challenge Louisville if his ankle allows him to play effectively.

Rihards Vavers — Memphis: His perimeter production could help keep the Tigers competitive.

Keys to the Game

Louisville must control the rebounding battle, maintain offensive balance and prevent Memphis from generating transition opportunities.

The Cardinals should exploit their frontcourt depth while limiting second-chance opportunities.

Memphis must protect the basketball, improve defensive communication and establish consistent perimeter scoring.

Turnovers, three-point shooting and rebounding could determine the outcome.

Betting Prediction

Louisville appears to possess the stronger overall roster, particularly in frontcourt depth and defensive efficiency.

However, Memphis has already demonstrated its ability to defeat quality opponents, including Iowa State.

Without a confirmed point spread or total, the strongest preliminary betting position is Louisville on the moneyline, subject to the available price.

Both offenses possess significant scoring potential, but Louisville’s defense and rebounding advantage could limit Memphis’ opportunities.

Best Bet: Louisville Moneyline — pending odds confirmation

The Verdict

Memphis’ best opportunity comes through Reid and Vavers creating explosive perimeter scoring opportunities.

However, Louisville possesses superior frontcourt depth and a more balanced offensive attack.

Expect Bidunga to control the paint while Shelstad distributes the basketball effectively.

Memphis remains competitive behind its home crowd, but Louisville’s rebounding advantage and offensive depth eventually prove decisive.

Final Score Prediction

Louisville Cardinals 86, Memphis Tigers 75

Picks Summary

Betting Category Pick Best Bet Louisville Moneyline, price pending Against the Spread Await confirmed line Moneyline Louisville Over/Under Await confirmed total Top Prop Flory Bidunga Over 7.5 Rebounds

Final Prediction: Louisville 86, Memphis 75

Louisville wins by 11 points, improving to 3-0, while Memphis falls to 2-2.

The projected 161 combined points reflect both programs’ offensive potential.

Louisville strengthens its national ranking with an important nonconference road victory at FedExForum.