Tonight, the St. Louis Cardinals (12–16) visit the Cincinnati Reds (15–13) at Great American Ball Park for the opener of a four-game series. First pitch is scheduled for 6:40 p.m. ET. The Reds are hot and the Cardinals are not headed into this series.
St. Louis Cardinals vs Cincinnati Reds
Run Line: Cardinals -1.5
Moneyline Cardinals -102
Moneyline Reds -116
Over/Under 9
These odds were updated at 9 am EST on 04/28/25, coming from DraftKings. Check out the
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Key Matchup Notes
Cardinals: Despite a strong team batting average, they’ve struggled to convert hits into runs, particularly on the road.
Reds: Coming off a sweep in Colorado, their offense showed signs of life, but overall consistency remains an issue.
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Cardinals vs Reds Moneyline
I think a moneyline bet is the best way to bet this game and I am leaning to the Reds as they are playing the better baseball as of right now, and they will score more runs.
DraftKings
4.6/5
Tip: Bet Reds ML
Bullpen will be a major key
Reds Hitting better
Reds at home
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Cardinals vs Reds Over/Under Analysis
I would lean towards the over in this game as the pitching matchup highly favors a high-scoring game.
DraftKings
4.6/5
Tip: Bet the Over 7.59
Cardinals Starting Pitcher will struggle
Reds are hot
Bullpen will be key
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Conclusion
Given the Reds’ offensive prowess and the Reds current hot streak, you have to feel comfortable betting the Reds tonight. Reds 8 Cardinals 4
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